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Manufacturer: Sun Pharmaceutical Industries Ltd
Pack size: 20 Tablet/s, 30 Tablet/s, 40 Tablet/s
Pharma Form: Tablet
Strength: 12 Mg
Uses: Anthelmintic & Anti-Worm
IntroductionIvermectol 12 mg
Ivermectol 12 mg contains ivermectin as its active ingredient. Ivermectin is a broad-spectrum antiparasitic agent often prescribed to humans to treat various parasitic infections, including certain worms as well as external parasites like mites and lice.
Active Ingredient – Ivermectin
Ivermectin belongs to a class of drugs called macrocyclic lactones. Although initially designed as a treatment for animal parasites, its effectiveness against human infections has made it an indispensable ally in tropical medicine. Ivermectin works by disrupting parasite nerve systems causing them to paralyse themselves before eventually dying off.
Indications and Applications
Ivermectol 12 mg is widely prescribed to treat various parasitic infections, such as:
1. Onchocerciasis (River Blindness): Ivermectin is an essential medication in controlling onchocerciasis, a parasitic disease caused by Onchocerca volvulus nematode infection transmitted through blackfly bites.
2. Strongyloidiasis: This intestinal infection is caused by Strongyloides stercoralis nematodes, and Ivermectin has proven its efficacy at treating both intestinal and disseminated forms of strongyloidiasis.
3. Scabies: Ivermectin can be prescribed to treat scabies, an infection caused by Sarcoptes scabiei mite.
4. Head Lice: Additionally, Ivermectin may also be used to treat head lice infestations (Pediculus humanus capitis).
Mechanism of Action
Ivermectin works by increasing the release of Gamma Aminobutyric Acid (GABA), an inhibitory neurotransmitter found in parasites. This leads to increased cell membrane permeability for chloride ions to enter, leading to hyperpolarization of their neuromuscular membrane and leading to paralysis and death for parasites.
Dosage and Administration
Healthcare providers prescribe Ivermectol 12 mg in doses determined by specific parasitic infections being treated, the patient's weight and other relevant factors. Usually it should be taken orally on an empty stomach with water as prescribed; adherence to this prescribed dosage will ensure its success in fighting the parasitic infections being treated.
Side Effects and Considerations
Though Ivermectin is generally well-tolerated, it may cause side effects. Common examples are dizziness, nausea and diarrhea. When used at higher dosages for other indications such as neurotoxicity it may cause more serious adverse reactions; patients are encouraged to report any unusual or severe reactions directly to their healthcare provider.
Global Impact in Parasite Control
Ivermectin has made an enormous contribution to global health, particularly in regions with high prevalence rates of parasitic infections such as onchocerciasis. Mass drug administration programs run in collaboration with organizations such as WHO have significantly decreased disease burden.
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