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Isentress 400 Mg


Generic:              Raltegravir
Manufacturer:   MSD Pharmaceuticals India Pvt Ltd
Pack size:          120 Tablet/s, 180 Tablet/s, 60 Tablet/s    
Pharma Form:   Tablet
Strength:            400 Mg
Uses:                  HIV

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Categories: HIV
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Isentress 400 mg: A Comprehensive Guide to Raltegravir in HIV Treatment

One of the most essential antiretroviral medications for the treatment of HIV infection is Isentress 400 mg, which contains the active ingredient raltegravir. Antiretroviral therapy (ART) is more effective when integrated inhibitors like Isentress reduce viral replication. Let's take a closer look at Isentress 400 mg, dissecting its functions, how it works, and how it fits into the modern HIV therapy scene.

Understanding Raltegravir

Isentress 400 mg is based on the integrase inhibitor raltegravir. As a result, it impedes the HIV replication cycle by preventing the virus from integrating its genetic material into the DNA of human immune cells. The anti-HIV drug Isentress slows the virus's spread by blocking this mechanism.

Uses of Isentress 400 mg

Both persons who have never had therapy for HIV and those who have been prescribed Isentress 400 mg as part of their HIV treatment regimen. To create a complete antiretroviral treatment regimen, it is frequently recommended alongside other ART drugs. Treating HIV with this medication helps keep the virus from replicating, supports the immune system, and stops the disease from progressing to AIDS.

Mechanism of Action

Isentress binds to and inhibits the HIV replication protein integrase, which is critical to its mode of action. As raltegravir blocks integrase, it stops the virus from inserting its DNA into the host immune cells. This interference makes the virus less capable of replicating, which helps to keep viral levels in the bloodstream low.

Significance in HIV Treatment

The efficacy and safety of Isentress have propelled it to the forefront of HIV treatment. It belongs to a newer family of antiretroviral medicines called integrase inhibitors, which have been effective against HIV strains that are resistant to previous medications. Isentress 400 mg's once-daily dosage increases its convenience and adherence, two elements that are critical for the effectiveness of long-term HIV care.

Administration and Dosage

The usual dosage of Isentress 400 mg is taken orally. However, this can change depending on the patient's condition. It is not necessary to eat before or after taking the drug. Nevertheless, for the best possible results from therapy, it is crucial to take the medication exactly as directed and listen to the advice of your doctor.

Caution and Considerations

People taking Isentress for HIV treatment should be aware of the possibility of adverse effects, even though the drug is usually well-tolerated. Symptoms such as nausea, exhaustion, and headache are common. It is also essential to keep track of any prescription interactions and let your healthcare professionals know immediately if you have any concerns or if your health condition changes.


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