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Dorzox T EyeDrop


Generic:              Dorzolamide / Timolol
Manufacturer:   Cipla Ltd
Pack size:          1 Eye Drop/s, 3 Eye Drop/s, 6 Eye Drop/s    
Pharma Form:   Eye Drop
Strength:            2% and 0.5%
Uses:                  Eye Care

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Categories: Eye Care
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What is Dorzox T Eye Drops

Dorzox T Eye Drops are a combination ophthalmic medication intended to regulate intraocular pressure (IOP). Consisting of two active ingredients, dorzolamide and timolol, this combination eye drop works in two ways to lower elevated intraocular pressure levels that contribute to progression of glaucoma.

Active Ingredients:

1. Dorzolamide: As a carbonic anhydrase inhibitor, dorzolamide works to decrease intraocular pressure by inhibiting carbonic anhydrase formation of bicarbonate ions that facilitate fluid secretion from the eye. By doing this, dorzolamide limits fluid production from being secreted from it into the eye itself and ultimately decreases production of aqueous humor production and subsequent intraocular pressure reduction.

2. Timolol: Timolol, an nonselective beta-adrenergic antagonist, further contributes to lowering intraocular pressure by decreasing production of aqueous humor. This effect is achieved by blocking beta receptors on ciliary epithelia cells thereby decreasing production of this type of fluid.

Indications: Dorzox T Eye Drops are intended to reduce intraocular pressure under specific circumstances:

1. Open-Angle Glaucoma: The most prevalent type of glaucoma, in which drainage angles remain open but outflow of aqueous humor becomes restricted, leading to elevated intraocular pressure and ultimately increased intraocular pressure.

2. Ocular Hypertension: Ocular hypertension refers to elevated intraocular pressure without optic nerve damage, raising the risk of developing glaucoma.

Mechanism of Action

Dorzox T is designed to deliver comprehensive intraocular pressure reduction by combining dorzolamide and timolol's combined mechanisms, specifically carbonic anhydrase inhibition in ciliary processes of the eye and beta receptor blockage to decrease both production and outflow of aqueous humor.

Dosage and Administration

 Ophthalmologists generally recommend prescribing Dorzox T Eye Drops according to the severity and response of their condition, with one or two drops administered into affected eye(s) as instructed by healthcare provider.

Contraindications and Precautions

Due to certain contraindications or precautions, Dorzox T Eye Drops should not be used by certain individuals, including those with asthma, severe chronic obstructive pulmonary disease (COPD), sinus bradycardia or heart block. Pregnant and breastfeeding mothers should only take Dorzox T under guidance from healthcare providers.

Side Effects 

Dorzox T Eye Drops can cause common side effects, including eye discomfort or burning, blurred vision, and bitter taste. Furthermore, respiratory problems or changes to heart rate could result from the presence of timolol. Patients must notify their healthcare provider of any persistent or severe side effects as soon as they occur.

Monitoring and Follow-up 

Monitoring and Follow-up: Dorzox T treatments require close observation of intraocular pressure and eye health during their course, with periodic exams by an ophthalmologist to monitor response to therapy and make adjustments as necessary.

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